What is protocol for isolation of trypsin?

trypsin is to be isolated from papaya.What is protocol for isolation of trypsin?
Trypsin is made by animals. (See the Wikipedia link below) There are proteases similar to trypsin made by papaya, such as papain. Papain is a protease, but has a different mechanism of action than trypsin. A brief method of purifying papain is at the Wikipedia site, below.