Friday, July 23, 2010

What is the role of sodium dodecylsulphate in the isolation of DNA?

how sodium dodecylsulphate act on membranes of cells ?What is the role of sodium dodecylsulphate in the isolation of DNA?
SDS or, Sodium Dodecyl Sulphate, is a detergent that ruptures the cell membrane by alkaline hydrolysis.





This provides an ease for the DNA to get released in the solution.What is the role of sodium dodecylsulphate in the isolation of DNA?
SDS solubilizes the membrane so that you can proceed with the DNA isolation
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